African Mango - NutraPedia

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African Mango: Health Benefits and Considerations

1. Conditions Studied

African Mango, known scientifically as Irvingia gabonensis, has been studied for various health conditions, particularly for weight loss, obesity, high cholesterol, and diabetes.

2. Efficacy in Treating Conditions

Research suggests that African Mango may have some positive effects on weight loss and fat reduction, possibly due to its fiber content, which can help to promote a feeling of fullness. Some studies have also indicated potential benefits in improving cholesterol levels and blood glucose control. However, these studies are not conclusive, and more research is needed to fully understand its efficacy.

3. Health Benefits

African Mango is associated with several health benefits, including:

Weight loss and reduced waist circumference
Improved lipid profiles, including reductions in total and LDL cholesterol
Better control of blood sugar levels
Increased satiety, which can help reduce calorie intake

4. Potential Downsides

While African Mango is generally considered safe, there are potential downsides, such as:

Mild side effects like flatulence, headaches, and sleep problems
Insufficient evidence to determine long-term safety and efficacy
Possible interactions with medications, particularly those for diabetes and high cholesterol

5. Genetic Variations and Effects

There is currently limited research on the interaction between African Mango and specific genetic variations. As genetic factors can influence individual responses to supplements, it is possible that certain genetic profiles may experience more or less benefit from African Mango. However, without substantial evidence, no definitive conclusions can be drawn at this time.

African Mango (Irvingia gabonensis) Overview

African Mango, also known as Irvingia gabonensis, is a fruit tree indigenous to tropical Africa. It is valued for both its wood and medicinal properties. The fruit's mesocarp is rich in phytochemicals, with a higher ascorbic acid concentration than many known vitamin C-rich fruits. It can be consumed in various forms, such as fresh, dried, as juice, wine, or as a flavoring agent.

The kernel's oil content is high, predominantly consisting of myristic and lauric acids, and solid at room temperature, making it suitable for diverse applications. The seed contains 41 phenolic compounds, with ellagic acid derivatives being predominant. The oil has a refractive index of 1.42, low free fatty acids, and peroxide value, suggesting high quality and potential for soap making.

Studies have shown that African Mango has nutritional benefits and health-promoting properties, particularly its pulp and seed. It has been popular in the U.S. for weight loss, with the Irvingia gabonensis seed extract (IGOB131) showing effectiveness in reducing body weight and improving metabolic parameters in overweight individuals. However, the effectiveness for weight loss remains unproven due to limited and poor-quality studies.

A new method for extracting lipids and gum from the seeds has been developed, offering a simpler, cost-effective, and safer process than traditional methods. African mango seed extracts have also demonstrated potential protective effects against heart damage caused by certain cancer drugs.

One case reported chronic kidney disease potentially associated with African mango consumption, but a 90-day toxicity study showed no adverse effects at high doses. African mango may inhibit fat cell development and could be used to manage obesity. Lastly, a major component isolated from its seeds, terminalin, exhibits antidiabetic properties by promoting glucose uptake in muscle cells.

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