Dental Implants - NutraPedia
Back to Table of Contents
Dental Implants Overview
1) Conditions Studied for Dental Implants
Dental implants have been studied for a variety of conditions, including:
- Tooth loss due to decay or trauma
- Periodontal diseases resulting in tooth loss
- Edentulism (complete loss of teeth)
- Oral cancers that necessitate surgical removal of teeth
- Congenital absence of teeth
2) Efficacy in Treating Conditions
Dental implants have proven to be effective in treating the above-mentioned conditions. They offer a permanent solution for tooth replacement and are widely regarded as a successful option for restoring functionality and aesthetics.
3) Health Benefits of Dental Implants
Dental implants offer several health benefits:
- Improved oral functionality, enabling proper chewing and digestion
- Prevention of bone loss in the jaw by providing stimulation through chewing
- Enhanced appearance and self-esteem
- Improved speech compared to other dental prosthetics
- Greater durability and longevity than other tooth replacement options
4) Potential Downsides of Dental Implants
While dental implants have many benefits, there are also potential downsides to consider:
- They require a surgical procedure, which carries inherent risks such as infection, nerve damage, or sinus problems
- Implants can be expensive and may not always be covered by dental insurance
- The process can be lengthy as it requires time for the bone to heal and integrate with the implant
- There is a possibility of implant failure or rejection
5) Dental Implants and Genetic Variations
Research on the effects of genetic variations on the success of dental implants is still evolving. Some studies suggest that certain genetic factors may influence the risk of peri-implantitis (inflammation around the implant) and implant failure. However, more research is needed to determine the extent to which genetic variations can affect implant outcomes.
Summary: Dental Implants and Genetic Influences
Dental implants are a common solution for tooth loss, and their success can be influenced by various factors, including genetic ones. Recent studies have explored the relationship between genetic polymorphisms and the risk of dental implant complications, such as peri-implantitis, which is an inflammatory condition that affects tissues around implants. The studies have investigated the association of specific single nucleotide polymorphisms (SNPs) with the risk of chronic periodontitis (CP), peri-implantitis (PI), and early implant failure.
Key Findings:
- Genetic polymorphisms in certain genes, including those related to inflammation and tissue remodeling, may influence the risk of dental implant complications.
- Some genetic variations, such as those in the IL-1 gene cluster, have been linked to an increased susceptibility to peri-implant diseases.
- Other studies suggest a potential link between low levels of serum vitamin D and increased marginal bone loss around implants.
- Additional research is needed to confirm the influence of genetic factors and to potentially develop personalized treatment strategies.
Conclusion:
While some genetic markers have been identified as potential risk factors for implant complications, the evidence is not yet conclusive. Future research with larger sample sizes and diverse populations is essential to better understand the genetic influences on dental implant success.
References:
- BRAF gene polymorphism (rs10487888) assessment in chronic periodontitis and peri-implantitis in an Iranian population
- IL-1RN gene polymorphism is associated with peri-implantitis
- Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis
- MMP-13 Polymorphism as a Risk Factor in Implant Loss
- Identification of key genes and pathways for peri-implantitis through the analysis of gene expression data
- Analysis of osteoprotegerin (OPG) gene polymorphism in Iranian patients with chronic periodontitis and peri-implantitis. A cross-sectional study
- Two neglected biologic risk factors in bone grafting and implantology: high low-density lipoprotein cholesterol and low serum vitamin D
- Peri-implant disease and chronic periodontitis: is interleukin-6 gene promoter polymorphism the common risk factor in a Brazilian population?
- The effect of interleukin-1 allele 2 genotype (IL-1a(-889) and IL-1b(+3954)) on the individual's susceptibility to peri-implantitis: case-control study
- Association between Interleukin-1 Polymorphisms and Susceptibility to Dental Peri-Implant Disease: A Meta-Analysis
- Influence of Serum Vitamin D Levels on Survival Rate and Marginal Bone Loss in Dental Implants: A Systematic Review
- Influence of epigenetics on periodontitis and peri-implantitis pathogenesis
- Association of Cytokine Gene Polymorphism with Peri-implantitis Risk
- Gene Correlation Network Analysis to Identify Biomarkers of Peri-Implantitis
- Reasons for marginal bone loss around oral implants
- RANK/RANKL/OPG gene polymorphisms and loss of orthodontic mini-implants
- Association Between Tumor Necrosis Factor-α (G-308A) Polymorphism and Chronic Periodontitis, Aggressive Periodontitis, and Peri-implantitis: A Meta-analysis
- Basis of bone metabolism around dental implants during osseointegration and peri-implant bone loss
- Association between IL-1A and IL-1B gene polymorphisms with peri-implantitis in a Portuguese population-a pilot study
- Role of proinflammatory mutations in peri-implantitis: systematic review and meta-analysis
- Analysis of the association of IL1B(C-511T) polymorphism with dental implant loss and the clusterization phenomenon
- Clinical consequences of IL-1 genotype on early implant failures in patients under periodontal maintenance
- A complete physical mapping of the vitamin D receptor gene for dental implant loss: A pilot study
- Evaluation of the relationship between interleukin-1 gene cluster polymorphisms and early implant failure in non-smoking patients
- Impact of IL-1 genotype and smoking status on the prognosis of osseointegrated implants
- On Peri-Implant Bone Loss Theories: Trying To Piece Together the Jigsaw
- Association of interleukin-1 gene polymorphism and early crestal bone loss around submerged dental implants: A systematic review and meta-analysis
- Immediate restoration of single implants placed immediately after implant removal. A case report
- Association of the composite IL-1 genotype with peri-implantitis: a systematic review
- Outcomes of placing dental implants in patients taking oral bisphosphonates: a review of 115 cases
- A comprehensive and critical review of dental implant prognosis in periodontally compromised partially edentulous patients
- Retrospective cohort study of 4,591 dental implants: Analysis of risk indicators for bone loss and prevalence of peri-implant mucositis and peri-implantitis
- A systematic review on the association between genetic predisposition and dental implant biological complications
- Interleukin-16 rs4072111 Polymorphism is Associated with the Risk of Peri-Implantitis in the Chinese Population
- The role of IL-1 gene polymorphisms (IL1A, IL1B, and IL1RN) as a risk factor in unsuccessful implants retaining overdentures
- Osteoprotegerin Gene (OPG) Polymorphisms Associated with Peri-implantitis Susceptibility in a Chinese Han Population
- Analysis of the association of IL4 polymorphisms with orthodontic mini-implant loss
- Association between Osteoprotegerin rs2073618 polymorphism and peri-implantitis susceptibility: a meta-analysis
- Influence of MMP-8 promoter polymorphism in early osseointegrated implant failure
- An Exploratory Case-Control Study on the Impact of IL-1 Gene Polymorphisms on Early Implant Failure
- Risk indicators for peri-implantitis. A narrative review
- Comparison of IKKI gene polymorphisms (rs1539243 and rs12728136) between chronic periodontitis and peri-implantitis patients in an Iranian population (a cross-sectional study)
- IL1 gene polymorphisms and unsuccessful dental implants
- Genetic association of the epidermal growth factor gene polymorphisms with peri-implantitis risk in Chinese population
- Genetic Polymorphisms Associated with Early Implant Failure: A Systematic Review
- Relationship between interleukin-1 genotype and peri-implantitis: a literature review
- MiR146a and MiR499 gene polymorphisms in Iranian periodontitis and peri-implantitis patients
- A systematic review of the incidence of biological and technical complications in implant dentistry reported in prospective longitudinal studies of at least 5 years
- Genetic and immunological markers predict titanium implant failure: a retrospective study
- Genetic Risk Factors for the Development of Periimplantitis
- Systematic review on the association between genetic polymorphisms and dental implant-related biological complications
- Is it possible to decrease the occurrence of dental implant failures through the use of preventative antibiotics?
- Current Molecular, Cellular and Genetic Aspects of Peri-Implantitis Disease: A Narrative Review
- Association of IL-10 and TNF-α Polymorphisms with Dental Peri-Implant Disease Risk: A Meta-Analysis, Meta-Regression, and Trial Sequential Analysis
- Assessment of IL-10, IL-1ß and TNF-α gene polymorphisms in patients with peri-implantitis and healthy controls
- Association between common polymorphisms in IL-1 and TNFα and risk of peri-implant disease: A meta-analysis
- Haptoglobin gene polymorphisms in peri-implantitis and chronic periodontitis
- Investigation of pathogenic genes in peri-implantitis from implant clustering failure patients: a whole-exome sequencing pilot study
- Vitamin D deficiency in early implant failure: two case reports
- Association between Genetic Polymorphisms in RANK, RANKL and OPG and Peri-Implant Diseases in Patients from the Amazon Region
- Low serum vitamin D and early dental implant failure: Is there a connection? A retrospective clinical study on 1740 implants placed in 885 patients
- The impact of genotypes and immune reactivity on peri-implant inflammation: Identification and therapeutic use of anti-inflammatory drugs and immunomodulators
- Analysis of RANKL gene polymorphism (rs9533156 and rs2277438) in Iranian patients with chronic periodontitis and periimplantitis
- Vitamin D Supplementation for Prevention of Dental Implant Failure: A Systematic Review
- Analysis of the association of TNF-α, IL-1A, and IL-1B polymorphisms with peri-implantitis in a Chinese non-smoking population
- Matrix metalloproteinases gene polymorphism haplotype is a risk factor to implant loss: A case-control study
- Haplotypes in BMP4 and FGF Genes Increase the Risk of Peri-Implantitis
- Risk of bias assessment of systematic reviews regarding dental implant placement in smokers: An umbrella systematic review
- Genetic susceptibility to dental implant failure: a critical review
- Current understanding of genetic polymorphisms as biomarkers for risk of biological complications in implantology
- Can Genetic Factors Compromise the Success of Dental Implants? A Systematic Review and Meta-Analysis
- Different contribution of BRINP3 gene in chronic periodontitis and peri-implantitis: a cross-sectional study
- Outcome of orthodontic mini-implant loss in relation to interleukin 6 polymorphisms
- Osseointegrated implant failure associated with MMP-1 promotor polymorphisms (-1607 and -519)
- Does vitamin D have an effect on osseointegration of dental implants? A systematic review
- Interventions for replacing missing teeth: treatment of peri-implantitis
- Meta-analysis of the association between common interleukin-1 polymorphisms and dental implant failure
- General genetic and acquired risk factors, and prevalence of peri-implant diseases - Consensus report of working group 1
- Association of interleukin 4 gene polymorphisms with dental implant loss
- Relationship between Genetic Polymorphisms with Periodontitis and Peri-Implantitis in the Iranian Population: A Literature Review
- Genetic Involvement in Dental Implant Failure: Association With Polymorphisms of Genes Modulating Inflammatory Responses and Bone Metabolism
- A comparative retrospective study of immediately loaded implants in postextraction sites versus healed sites: results after 6 to 7 years in the maxilla
- CD14 and TNFα single nucleotide polymorphisms are candidates for genetic biomarkers of peri-implantitis
- Association of haptoglobin and natural resistance-associated macrophage protein 1 alleles with heme-consuming periodontal pathogens in chronic periodontitis and peri-implantitis: A pilot study
- Is Low Serum Vitamin D Associated with Early Dental Implant Failure? A Retrospective Evaluation on 1625 Implants Placed in 822 Patients
- The Relationship Between Low Serum Vitamin D Level and Early Dental Implant Failure: A Systematic Review
- Chemokine Receptor 2 (CXCR2) Gene Polymorphisms and Their Association with the Risk of Developing Peri-Implantitis in Chinese Han Population
- Associations between peri-implant crevicular fluid volume, concentrations of crevicular inflammatory mediators, and composite IL-1A -889 and IL-1B +3954 genotype. A cross-sectional study on implant recall patients with and without clinical signs of peri-implantitis
- Recent advancements in regenerative dentistry: A review
- TRAF family member-associated NF-KB activator (TANK) gene polymorphism in chronic periodontitis and peri-implantitis patients
- The effect of static load on dental implant survival: a systematic review
- Clinical aspects and polymorphisms in the LTA, TNFA, LTB genes and association with dental implant loss
- What impact do systemically administrated bisphosphonates have on oral implant therapy? A systematic review
- Identification of Potential Genetic Biomarkers and Target Genes of Peri-Implantitis Using Bioinformatics Tools
- Genetic polymorphisms of the interleukin-1 gene and early marginal bone loss around endosseous dental implants
- A comparative study of the role of cytokine polymorphisms interleukin-10 and tumor necrosis factor alpha in susceptibility to implant failure and chronic periodontitis
- New and innovative biomaterials, techniques and therapy concepts: Biologization in maxillofacial surgery, oral surgery and dentistry is in full swing. PRF, PRGF, PRP, blood plasma-stabilized augmentations, supplementation of micronutrients and vitamins - what opportunities do such "biological" approaches actually offer? We introduce them here
- Analysis of the association of IL1B (C+3954T) and IL1RN (intron 2) polymorphisms with dental implant loss in a Brazilian population
- Comparative evaluation of crestal bone level in patients having low level of Vitamin D treated with dental implant with or without Vitamin D3 supplements
- The relationship between single nucleotide polymorphisms and dental implant loss: a scoping review
- Prevalence and Possible Risk Factors of Peri-implantitis: A Concept Review
- Advanced Biomaterials and Techniques for Oral Tissue Engineering and Regeneration-A Review
- Association between tumor necrosis factor-alpha G-308A polymorphism and dental peri-implant disease risk: A meta-analysis
- Analysis of MMP-1 and MMP-9 promoter polymorphisms in early osseointegrated implant failure
- Analysis of association of clinical aspects and vitamin D receptor gene polymorphism with dental implant loss
Upload Whole Genome Sequencing (WGS) raw DNA data today and take a deep dive into your genome!
Or if you only have standard microarray data currently, upload raw DNA data to get started with your free DNA raw data analysis today!